Accessibility for Ontarians with Disabilities Act (AODA) Practice Exam

What causes the euphoria experienced under the influence of cocaine?

1. A cascade-effect of endorphins

2. A sudden release of adrenalin

3. Increased basal metabolic rate

4. A buildup of neurotransmitters

The correct answer is: A buildup of neurotransmitters

The euphoria associated with cocaine use primarily results from a buildup of neurotransmitters, particularly dopamine, in the brain. When cocaine is consumed, it inhibits the reuptake of dopamine in the synapses, leading to an accumulation of this neurotransmitter. Dopamine plays a crucial role in the brain's reward system, and its increased levels are responsible for the intense pleasurable feelings and euphoric highs experienced by individuals using cocaine. This mechanism highlights how cocaine alters the normal signaling pathways in the brain, leading to amplified feelings of pleasure and reinforcement of drug-seeking behaviors. The more dopamine is present in the synaptic cleft, the stronger the signal sent to the brain's reward centers, creating a powerful feeling of euphoria. While other physiological responses, such as increased adrenaline and metabolic changes, are also associated with cocaine use, the direct cause of the euphoria is linked to the neurotransmitter dynamics rather than solely to adrenaline release or metabolic rate alterations.