Accessibility for Ontarians with Disabilities Act (AODA) Practice Exam

Which disorder is most commonly associated with disulfiram?

1. Opioid dependence

2. Alcohol dependence

3. Cocaine dependence

4. Narcotic dependence

The correct answer is: Alcohol dependence

Disulfiram is a medication primarily used in the treatment of alcohol dependence. It works by inhibiting the enzyme acetaldehyde dehydrogenase, which leads to unpleasant reactions when alcohol is consumed, thereby discouraging further drinking. This disulfiram-alcohol reaction can include symptoms such as flushing, nausea, and palpitations, providing a strong aversion to alcohol use. The goal of disulfiram therapy is to support individuals in their recovery from alcohol addiction by fostering a significant negative association with alcohol consumption. In contrast, the other disorders listed do not have a direct relationship with disulfiram. Opioid dependence is treated with a range of other medications, such as methadone or buprenorphine, which are designed to manage withdrawal symptoms and cravings. Cocaine dependence is commonly addressed through behavioral therapies and no specific pharmacological treatment is as established as disulfiram is for alcohol dependence. Narcotic dependence generally refers to opiate addiction, which itself is distinct from alcohol dependence and treated through various other methods, emphasizing the specific role that disulfiram plays in managing alcohol use disorder.